Drug layer coating on pellet:
1. Selection plate size based on Pellet size
2. Batch size (initial bed load) to finalized based on required weigh build up.(example initial load :30% to final load 75% considering 150% weight build up)
3. solid content of drug solution based on available gun orifice size.(10-18%)
4. Overage of drug solution based on equipment efficiency to achieve 100% assay
CPPs:
1. CFM, Spray rate, droplet size, bed temperature, RH(dew point), Wurster column height etc.