PPI

Over-utilization of Proton-Pump Inhibitors

Over-utilization of Proton-Pump Inhibitors

Proton pump inhibitors (PPIs) are among the most commonly used medications in the world. Developed for the treatment and prevention of acid-mediated upper gastrointestinal conditions, these agents are being used increasingly for indications where their benefits are less certain and for indeterminate durations. Long-term PPI use has been associated with several safety concerns: All patients…