Melting Point Database (K-Z)

The terms melting range, melting point, or melting temperature are all used in pharmacopeial contexts at which a given solid material changes from a solid state to a liquid, or melts.


This is an open melting point database of pharmaceutical API and excipients. It will be helpful for characterization and purity evaluation of a molecule and also for solubility prediction of a drug candidate.


A list of pharmaceutical API and excipients with their melting point

  • Ketoprofen: Melting point is about 92°C–97°C

  • Ketorolac Tromethamine: Melting point is about 165°C–170°C

  • Labetalol Hydrochloride: Melting point is about 180°C

  • Lactobionic Acid: Melting point is about 130°C

  • Lactose, Monohydrate: Melting point is about 201°C-202°C

  • Lamivudine: Melting point is about 176°C

  • Lansoprazole: Melting point is about 166°C

  • Levonorgestrel: Melting point is about 232°C–239°C

  • Lisinopril: Melting point is about 160°C

  • Loperamide Hydrochloride: Melting point is about 225°C

  • Magnesium Stearate: Melting point is about 117°C-150°C

  • Malic Acid: Melting point is about 130°C

  • Mannitol: Melting point is about 165°C–170°C

  • Mebendazole: Melting point is about 290°C

  • Medroxyprogesterone Acetate: Melting point is about 205°C

  • Mefenamic Acid: Melting point is about 230°C

  • Megestrol Acetate: Melting point is about 213°C–220°C

  • Meglumine: Melting point is about 128°C–132°C

  • Menthol: Melting point is about 41°C–44°C

  • Mercaptopurine: Melting point is about 308°C

  • Methazolamide: Melting point is about 213°C

  • Methenamine: Melting point is about 260°C

  • Methocarbamol: Melting point is about 94°C

  • Methotrimeprazine: Melting point is about 126°C

  • Methylparaben: Melting point is about 125°C–128°C

  • Methylprednisolone: Melting point is about 240°C

  • Methylprednisolone Acetate: Melting point is about 225°C

  • Methylsulfonylmethane: Melting point is about 109°C

  • Miconazole: Melting point is about 78°C–88°C

  • Mometasone Furoate: Melting point is about 220°C

  • Naproxen Sodium: Melting point is about 255°C

  • Niacin: Melting point is about 235°C

  • Nitrofurazone: Melting point is about 236°C

  • Norepinephrine Bitartrate: Melting point is about 98°C–104°C

  • Oxandrolone: Melting point is about 225°C

  • Oxymetazoline Hydrochloride: Melting point is about 300°C

  • Oxyquinoline Sulfate: Melting point is about 185°C

  • Pentobarbital: Melting point is about 116°C

  • Phentolamine Mesylate: Melting point is about 178°C

  • Phenytoin: Melting point is about 295°C

  • Pilocarpine: Melting point is about 34°C

  • Poloxamer 124: Melting point is about 16°C

  • Poloxamer 188: Melting point is about 52°C

  • Poloxamer 407: Melting point is about 56°C

  • Polyoxyl Stearate: Melting point is about 26°C–60°C (based on the ethylene oxide unit and hydroxyl value)

  • Potassium Sorbate: Melting point is about 270°C

  • Prednisolone: Melting point is about 235°C

  • Prednisone: Melting point is about 230°C

  • Procyclidine Hydrochloride: Melting point is about 225°C

  • Progesterone: Melting point is about 121°C

  • Propranolol Hydrochloride: Melting point is about 164°C

  • Propylparaben: Melting point is about 96°C–99°C

  • Repaglinide: Melting point is about 132°C–136°C

  • Riboflavin: Melting point is about 280°C

  • Roxadustat: Melting point is about 200°C -215°C

  • Silver (Ag): Melting point is about 961 °C

  • Sodium Bicarbonate: Melting point is about 270°C

  • Sodium Chloride: Melting point is about 801°C

  • Scopolamine Hydrobromide: Melting point is about 197°C

  • Stearic Acid: Melting point is about 69°C-70°C

  • Succinylcholine Chloride: Melting point is about 160°C

  • Sucralose: Melting point is about 130°C

  • Sulfamethazine: Melting point is about 197°C–200°C

  • Sulfamethizole: Melting point is about 208°C–212°C

  • Sulfasalazine: Melting point is about 255°C

  • Sulisobenzone: Melting point is about 145°C

  • Sunflower Oil: Melting point is about 40°C–60°C

  • Tamoxifen Citrate: Melting point is about 142°C

  • Tamsulosin Hydrochloride: Melting point is about 230°C

  • Temazepam: Melting point is about 157°C–163°C

  • Tetrahydrozoline Hydrochloride: Melting point is about 256°C

  • Thiamine Hydrochloride: Melting point is about 248°C

  • Titanium Dioxide: Melting point is about 1855°C

  • Tolazamide: Melting point is about 161°C–173°C

  • Trazodone Hydrochloride: Melting point is about 231°C–234°C

  • Trichlormethiazide: Melting point is about 274°C

  • Triclosan: Melting point is about 57°C

  • Trihexyphenidyl Hydrochloride: Melting point is about 250°C

  • Trimethoprim Sulfate: Melting point is about 210°C–215°C

  • Trioxsalen: Melting point is about 230°C

  • Triprolidine Hydrochloride: Melting point is about 115°C

  • Uracil: Melting point is about 300°C

  • Ursodiol: Melting point is about 200°C–205°C

  • Vanillin: Melting point is about 81°C–83°C

  • Vitamin E: Melting point is about 70°C–75°C

  • Water: Melting point is about 0°C

  • Xanthan Gum: Melting point is about 270°C

  • Xylitol: Melting point is about 70°C–75°C

  • Zidovudine: Melting point is about 124°C


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