[FRD]

How to calculate the cross sectional surface area of fluid bed processor (FBP) for scale up?

[Pharma Digests]

You can follow the below equation-
A = πr^2

Where,
A= cross sectional surface area (m^2)
r= radious of the bottom screen (m)

[FRD]

Which parameters can keep same/similar during FBP process scale-up?

[Pharma Digests]

Following FBP parameters you can remain same/similar in both R&D and Production scale:
– Inlet air temperature
– Product temperature
– Atomization nozzle size

And you should adjust the below parameters:
– Inlet air flow
– Spray rate
– Atomization air pressure

[Author]

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