Melting Point Database (A-J)

The terms melting range, melting point, or melting temperature are all used in pharmacopeial contexts at which a given solid material changes from a solid state to a liquid, or melts.


This is an open melting point database of pharmaceutical API and excipients. It will be helpful for characterization and purity evaluation of a molecule and also for solubility prediction of a drug candidate.


A list of pharmaceutical API and excipients with their melting point

  • Acebutolol Hydrochloride: Melting point is about 141°C–144°C

  • Acetaminophen (Paracetamol): Melting point is about 168°C–172°C

  • Acetanilide: Melting point is about 114°C

  • Acetic Acid (Glacial): Melting point is about 17°C

  • Acetone: Melting point is about 94.3°C

  • Acetylcholine Chloride: Melting point is about 149°C–152°C

  • Acyclovir: Melting point is about 250°C

  • Adenosine: Melting point is about 235°C

  • Albuterol: Melting point is about 156°C

  • Alcohol: Melting point is about -112°C

  • Alfentanil Hydrochloride: Melting point is about 136°C–143°C (anhydrous), 116°C–126°C (monohydrate)

  • Allantoin: Melting point is about 225°C

  • Alprazolam: Melting point is about 225°C

  • Alprostadil: Melting point is about 110°C

  • Aminocaproic Acid: Melting point is about 205°C

  • Aminohippuric Acid: Melting point is about 195°C

  • Ascorbic Acid (Vitamin C): Melting point is about 190°C

  • Asparagine: Melting point is about 234°C

  • Aspartame: Melting point is about 246°C

  • Aspirin: Melting point is about 135°C

  • Atenolol: Melting point is about 146°C–148°C

  • Bendroflumethiazide: Melting point is about 220°C

  • Benoxinate Hydrochloride: Melting point is about 158°C

  • Benzalkonium Chloride: Melting point is about 40°C

  • Benzoic Acid: Melting point is about 122°C

  • Betahistine Hydrochloride: Melting point is about 151°C–154°C

  • Betamethasone: Melting point is about 240°C

  • Bismuth Citrate: Melting point is about 300°C

  • Bronopol: Melting point is about 128°C-132°C

  • Bupivacaine Hydrochloride: Melting point is about 248°C

  • Butoconazole Nitrate: Melting point is about 160°C

  • Butorphanol Tartrate: Melting point is about 217°C–219°C

  • Butylated Hydroxyanisole: Melting point is about 47°C

  • Butylated Hydroxytoluene: Melting point is about 70°C

  • Butylparaben: Melting point is about 68°C–71°C

  • Calcium Chloride: Melting point is about 772°C

  • Calcium Carbonate: Melting point is about 825°C

  • Camphor: Melting point is about 174°C–179°C

  • Capsaicin: Melting point is about 65°C

  • Captopril: Melting point is about 104°C–110°C

  • Carboxymethylcellulose Sodium: Melting point is about 230°C

  • Castor Oil: Melting point is about -12°C

  • Castor Oil (Hydrogenated): Melting point is about 83°C – 88°C

  • Cefazolin: Melting point is about 198°C–200°C

  • Cellulose (Microcrystalline): Melting point is about 260°C-270°C

  • Cellulose Acetate Phthalate: Melting point is about 192°C

  • Cetostearyl Alcohol: Melting point is about 49°C-56°

  • Cetyl Alcohol: Melting point is about 45°C–50°C

  • Chlorambucil: Melting point is about 65°C–69°C

  • Chlorhexidine: Melting point is about 132°C-134°C

  • Chlordiazepoxide: Melting point is about 240°C

  • Chlorobutanol: Melting point is about 95°C (anhydrous); 76°C (hydrous)

  • Chlorodifluoroethane (HCFC): Melting point is about -131°C

  • Chloroquine Phosphate: Melting point is about 193°C–215°C

  • Chlorothiazide: Melting point is about 340°C

  • Chlorpromazine: Melting point is about 60°C

  • Chlorthalidone: Melting point is about 215°C

  • Cholecalciferol: Melting point is about 85°C

  • Citric Acid (Anhydrous): Melting point is about 153°C

  • Citric Acid Monohydrate: Melting point is about 100°C

  • Clofazimine: Melting point is about 217°C

  • Clonazepam: Melting point is about 237°C–240°C

  • Clonidine: Melting point is about 130°C

  • Clotrimazole: Melting point is about 142°C

  • Cocoa Butter: Melting point is about 31°C–35°C

  • Colloidal Silicon Dioxide: Melting point is about 1600°C

  • Copovidone: Melting point is about 140°C

  • Cortisone Acetate: Melting point is about 240°C

  • Cyclizine Hydrochloride: Melting point is about 285°C

  • Cyclodextrins: Melting point is about 240°C-260°C

  • Cyclopentolate Hydrochloride: Melting point is about 138°C

  • Danazol: Melting point is about 225°C

  • Daprodustat: Melting point is about 240°C

  • Desipramine Hydrochloride: Melting point is about 213°C

  • Dexamethasone: Melting point is about 250°C

  • Dexbrompheniramine Maleate: Melting point is about 105°C–113°C

  • Dextromethorphan Hydrobromide: Melting point is about 126°C

  • Diazepam: Melting point is about 131°C–135°C

  • Diclofenac Sodium: Melting point is about 284°C

  • Digitonin: Melting point is about 230°C

  • Diltiazem Hydrochloride: Melting point is about 210°C

  • Dimethyl Sulfoxide: Melting point is about 18.4°C

  • Disodium Edetate: Melting point is about 250°C

  • Disopyramide Phosphate: Melting point is about 205°C

  • Dopamine Hydrochloride: Melting point is about 240°C

  • Doxapram Hydrochloride: Melting point is about 220°C

  • Doxylamine Succinate: Melting point is about 103°C–108°C

  • Droperidol: Melting point is about 145°C

  • Dydrogesterone: Melting point is about 167°C–171°C

  • Edetic Acid: Melting point is about 220°C

  • Enalapril Maleate: Melting point is about 144°C

  • Ephedrine: Melting point is about 33°C–40°C

  • Ergotamine Tartrate: Melting point is about 180°C

  • Estriol: Melting point is about 280°C

  • Estrone: Melting point is about 260°C

  • Ethyl Vanillin: Melting point is about 76°C-78°C

  • Fenofibrate: Melting point is about 79°C–82°C

  • Fentanyl Citrate: Melting point is about 150°C

  • Finasteride: Melting point is about 257°C

  • Flunisolide: Melting point is about 245°C

  • Fluocinolone Acetonide: Melting point is about 270°C

  • Fluorometholone: Melting point is about 280°C

  • Fluphenazine Decanoate: Melting point is about 30°C–32°C

  • Fluphenazine Hydrochloride: Melting point is about 225°C

  • Flurazepam Hydrochloride: Melting point is about 212°C

  • Fructose: Melting point is about 102°C-105°C

  • Fumaric Acid: Melting point is about 287°C

  • Gluconolactone: Melting point is about 153°C

  • Glyceryl Dibehenate: Melting point is about 70°C

  • Glyceryl Monostearate: Melting point is about 55°C-60°C

  • Glyceryl Tristearate: Melting point is about 69°C–73°C

  • Gold (Au): Melting point is about 1064°C

  • Hydralazine Hydrochloride: Melting point is about 275°C

  • Hydrocortisone: Melting point is about 215°C

  • Hydrocortisone Acetate: Melting point is about 220°C

  • Hydroxychloroquine Sulfate: Melting point is about 198°C

  • Hydroxypropyl Cellulose: Melting point is about 260°C-275°C

  • Hydroxypropyl Cellulose (Low-substituted): Melting point is about 290°C

  • Hyoscyamine Sulfate: Melting point is about 200°C

  • Hypromellose (HPMC): Melting point is about 220°C-230°C

  • Ifosfamide: Melting point is about 40°C

  • Indapamide: Melting point is about 167°C–170°C

  • Indomethacin: Melting point is about 162°C

  • Iron: Melting point is about 1538°C

  • Iron Oxides: Melting point is about 1565°C

  • Isopropyl Alcohol (IPA): Melting point is about -88.5°C


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