This pharmaceutical solubility database contains the aqueous and chemical solubility of API and Excipients commonly used in pharmaceutical industry.
- Famotidine solubility – very slightly soluble in water.
- Felodipine solubility – freely soluble in acetone and in methanol; very slightly soluble in heptane; insoluble in water.
- Fenbendazole solubility – practically insoluble in water.
- Fenofibrate solubility – practically insoluble in water.
- Fenoprofen Calcium solubility – slightly soluble in n-hexanol, in methanol, and in water.
- Fentanyl Citrate solubility – soluble in methanol; sparingly soluble in water; slightly soluble in chloroform.
- Ferric Oxide solubility – insoluble in water and in organic solvents.
- Ferric Sulfate solubility – slightly soluble in water and in ethanol (96%); practically insoluble in acetone and in ethyl acetate.
- Ferrous Sulfate solubility – very soluble in boiling water; freely soluble in water; insoluble in alcohol.
- Fexofenadine Hydrochloride solubility – freely soluble in methanol; very slightly to slightly soluble in water; very slightly soluble in acetone.
- Fluconazole solubility – freely soluble in methanol; soluble in alcohol and in acetone; sparingly soluble in isopropanol and in chloroform; slightly soluble in water.
- Fluorouracil solubility – sparingly soluble in water; slightly soluble in alcohol; practically insoluble in chloroform and in ether.
- Fluoxetine Hydrochloride solubility – freely soluble in alcohol and in methanol; sparingly soluble in water and in dichloromethane; practically insoluble in ether.
- Fluphenazine Decanoate solubility – very soluble in chloroform, in ether, in cyclohexane, in dehydrated alcohol, and in methylene chloride; freely soluble in methanol; insoluble in water.
- Fluvastatin Sodium solubility – soluble in alcohol, in methanol, and in water.
- Fluvoxamine Maleate solubility – freely soluble in alcohol and in chloroform; sparingly soluble in water; and practically insoluble in diethyl ether.
- Folic Acid solubility – very slightly soluble in water.
- Fructose solubility – freely soluble in water; soluble in alcohol and in methanol.
- Fumaric Acid solubility – soluble in alcohol; slightly soluble in water and in ether; very slightly soluble in chloroform.
- Furosemide solubility – sparingly soluble in alcohol; slightly soluble in ether; very slightly soluble in chloroform; practically insoluble in water.
- Gabapentin solubility – Freely soluble in water and in alkaline and acidic solutions.
- Galactose solubility – Soluble in water; very slightly soluble in alcohol.
- Gamma Cyclodextrin solubility – freely soluble in water and in propylene glycol; very slightly soluble in alcohol.
- Gelatin solubility – insoluble in cold water, but swells and softens when immersed in it.
- Gentamicin Sulfate solubility – Freely soluble in water; insoluble in alcohol, in acetone, in chloroform, in ether, and in benzene.
- Glimepiride solubility – slightly soluble in methanol; practically insoluble in water.
- Glutamine solubility – soluble in water; practically insoluble in alcohol and in ether.
- Glycopyrrolate solubility – soluble in water and in alcohol; practically insoluble in chloroform and in ether.
- Guaifenesin solubility – soluble in water, in alcohol, in chloroform, and in propylene glycol; sparingly soluble in glycerin.
- Haloperidol solubility – sparingly soluble in alcohol; slightly soluble in ether; practically insoluble in water.
- Halothane solubility – slightly soluble in water.
- Histidine solubility – soluble in water; very slightly soluble in alcohol; insoluble in ether.
- Hydralazine Hydrochloride solubility – soluble in water; slightly soluble in alcohol; very slightly soluble in ether.
- Hydrochlorothiazide solubility – very slightly soluble in water; sparingly soluble in methanol; insoluble in ether, in chloroform, and in dilute mineral acids.
- Hydrocodone Bitartrate solubility – soluble in water; slightly soluble in alcohol; insoluble in ether and in chloroform.
- Hydrocortisone solubility – sparingly soluble in acetone and in alcohol; slightly soluble in chloroform; very slightly soluble in water and in ether.
- Hydroxypropyl Cellulose solubility – soluble in cold water, in alcohol, in chloroform, and in propylene glycol, giving a colloidal solution; insoluble in hot water.
- Low-Substituted Hydroxypropyl Cellulose solubility – practically insoluble in alcohol and in ether; swells in water.
- Hypromellose (HPMC) solubility – swells in water and produces a clear to opalescent, viscous, colloidal mixture.
- Hypromellose Phthalate solubility – practically insoluble in water, in dehydrated alcohol, and in hexane.
- Ibandronate Sodium solubility – freely soluble in water; practically insoluble in methanol and in organic solvents.
- Ibuprofen solubility – very soluble in alcohol, in methanol, in acetone, and in chloroform; slightly soluble in ethyl acetate; practically insoluble in water.
- Ifosfamide solubility – very soluble in alcohol, in ethyl acetate, in isopropyl alcohol, in methanol, and in methylene chloride; freely soluble in water; very slightly soluble in hexanes.
- Imipramine Hydrochloride solubility – freely soluble in water and in alcohol; insoluble in ether and in benzene.
- Indinavir Sulfate solubility – freely soluble in water; soluble in methanol; practically insoluble in heptane.
- Indomethacin solubility – sparingly soluble in alcohol, in chloroform, and in ether; practically insoluble in water.
- Insulin solubility – soluble in solutions of dilute acids and alkalies.
- Inulin solubility – soluble in hot water; slightly soluble in cold water and in organic solvents.
- Iodine solubility – soluble in alcohol and in solutions of iodides; sparingly soluble in glycerin; very slightly soluble in water.
- Isobutyl Alcohol solubility – soluble in water.
- Isoniazid solubility – freely soluble in water; sparingly soluble in alcohol; slightly soluble in chloroform; very slightly soluble in ether.
- Isopropyl Isostearate solubility – insoluble in water.
- Isopropyl Myristate solubility – freely soluble in 90% alcohol; insoluble in water, in glycerin, and in propylene glycol.
- Isopropyl Palmitate solubility – insoluble in water, in glycerin, and in propylene glycol.
- Itraconazole solubility – sparingly soluble in tetrahydrofuran; very slightly soluble in alcohol; practically insoluble in water.
- Ivermectin solubility – practically insoluble in hexane and in water.
- Kaolin solubility – insoluble in water, in cold dilute acids, and in solutions of alkali hydroxides.
- Ketorolac Tromethamine solubility – freely soluble in water and in methanol; slightly soluble in alcohol.
- Lacosamide solubility – freely soluble in methanol; soluble in anhydrous ethanol; sparingly soluble in water; slightly soluble in acetonitrile; and practically insoluble in heptane.
- Lactic Acid solubility – miscible with water, with alcohol, and with ether.
- Anhydrous Lactose solubility – freely soluble in water; practically insoluble in alcohol.
- Lactose Monohydrate solubility – freely but slowly soluble in water; practically insoluble in alcohol.
- Lanolin solubility – freely soluble in ether and in chloroform; soluble in hot alcohol; sparingly soluble in cold alcohol; insoluble in water.
- Lansoprazole solubility – practically insoluble in water.
- Latanoprost solubility – practically insoluble in water.
- Lauric Acid solubility – very soluble in alcohol, in ether, and in methanol; soluble in acetone; practically insoluble in water.
- Lecithin solubility – practically insoluble in water, but it readily hydrates to form emulsions.
- Letrozole solubility – freely soluble in dichloromethane; slightly soluble in alcohol; practically insoluble in water.
- Leucine solubility – sparingly soluble in water; insoluble in ether.
- Levetiracetam solubility – very soluble in water; soluble in acetonitrile; practically insoluble in hexane.
- Levobunolol Hydrochloride solubility – soluble in water and in methanol; slightly soluble in alcohol and in chloroform.
- Levocetirizine Dihydrochloride solubility – freely soluble in water and in methanol.
- Levodopa solubility – slightly soluble in water; insoluble in alcohol.
- Levofloxacin solubility – sparingly soluble in water, in acetone, and in methanol; practically insoluble in glycerin and in n-octanol.
- Levonorgestrel solubility – slightly soluble in alcohol; practically insoluble in water.
- Levothyroxine Sodium solubility – slightly soluble in alcohol; very slightly soluble in water; insoluble in acetone, in chloroform, and in ether.
- Lidocaine solubility – very soluble in alcohol and in chloroform; freely soluble in benzene and in ether; practically insoluble in water.
- Linezolid solubility – sparingly soluble in acetone, in ethanol, and in methanol; very slightly soluble in water.
- Lisinopril solubility – soluble in water; sparingly soluble in methanol; practically insoluble in alcohol, in acetone, in acetonitrile, and in chloroform.
- Lithium Citrate solubility – freely soluble in water; slightly soluble in alcohol.
- Loperamide Hydrochloride solubility – freely soluble in methanol and in chloroform; slightly soluble in water and in dilute acids; very slightly soluble in isopropyl alcohol.
- Lopinavir solubility – freely soluble in methanol and alcohol; soluble in isopropanol; practically insoluble in water.
- Loratadine solubility – freely soluble in acetone, in chloroform, in methanol, and in toluene; insoluble in water.
- Lorazepam solubility – sparingly soluble in alcohol; slightly soluble in chloroform; insoluble in water.
- Losartan Potassium solubility – freely soluble in water; sparingly soluble in isopropyl alcohol; slightly soluble in acetonitrile.
- Lysine Acetate solubility – freely soluble in water.
- Lysine Hydrochloride solubility – freely soluble in water.
- Mafenide Acetate solubility – freely soluble in water.
- Magaldrate solubility – soluble in dilute solutions of mineral acids; insoluble in water and in alcohol.
- Magnesium Oxide solubility – practically insoluble in water; insoluble in alcohol.
- Magnesium Silicate solubility – insoluble in water and in alcohol. Is readily decomposed by mineral acids.
- Magnesium Trisilicate solubility – insoluble in water and in alcohol.
- Magnesium Stearate solubility – insoluble in water, in alcohol, and in ether.
- Malathion solubility – slightly soluble in water.
- Maltodextrin solubility – freely soluble or readily dispersible in water; slightly soluble to insoluble in anhydrous alcohol.
- Mannitol solubility – freely soluble in water; soluble in alkaline solutions; slightly soluble in pyridine; very slightly soluble in alcohol; practically insoluble in ether.
- Mebendazole solubility – freely soluble in formic acid; practically insoluble in water, in dilute solutions of mineral acids, in alcohol, in ether, and in chloroform.
- Meclizine Hydrochloride solubility – slightly soluble in dilute acids and in alcohol; practically insoluble in water and in ether; freely soluble in chloroform, in pyridine, and in acid-alcohol-water mixtures.
- Mefenamic Acid solubility – sparingly soluble in chloroform; slightly soluble in alcohol and in methanol; practically insoluble in water.
- Megestrol Acetate solubility – very soluble in chloroform; soluble in acetone; sparingly soluble in alcohol; slightly soluble in ether and in fixed oils; insoluble in water.
- Meglumine solubility – freely soluble in water; sparingly soluble in alcohol.
- Memantine Hydrochloride solubility – slightly soluble in water.
- Mercaptopurine solubility – soluble in hot alcohol and in dilute alkali solutions; slightly soluble in 2 N sulfuric acid; insoluble in water, in acetone, and in ether.
- Meropenem solubility – soluble in dimethylformamide and in 5% dibasic potassium phosphate solution; sparingly soluble in water and in 5% monobasic potassium phosphate solution; practically insoluble in alcohol, in acetone, in methylene chloride, and in ether.
- Metformin Hydrochloride solubility – freely soluble in water; slightly soluble in alcohol; practically insoluble in acetone and in methylene chloride.
- Methadone Hydrochloride solubility – freely soluble in alcohol and in chloroform; soluble in water; practically insoluble in ether and in glycerin.
- Methazolamide solubility – soluble in dimethylformamide; slightly soluble in acetone; very slightly soluble in water and in alcohol.
- Methenamine solubility – freely soluble in water; soluble in alcohol and in chloroform.
- Methimazole solubility – freely soluble in water, in alcohol, and in chloroform; slightly soluble in ether.
- Methocarbamol solubility – soluble in alcohol only with heating; sparingly soluble in water and in chloroform; insoluble in benzene and in n-hexane.
- Methyl Salicylate solubility – soluble in alcohol and in glacial acetic acid; slightly soluble in water.
- Methylcellulose solubility – soluble in glacial acetic acid and in a mixture of equal volumes of alcohol and chloroform; insoluble in alcohol, in ether, and in chloroform.
- Methyldopa solubility – very soluble in 3 N hydrochloric acid; sparingly soluble in water; slightly soluble in alcohol; practically insoluble in ether.
- Methylparaben solubility – freely soluble in alcohol and in methanol; slightly soluble in water.
- Methylparaben Sodium solubility – freely soluble in water; sparingly soluble in alcohol; insoluble in fixed oils.
- Methylprednisolone solubility – sparingly soluble in alcohol, in dioxane, and in methanol; slightly soluble in acetone and in chloroform; very slightly soluble in ether; practically insoluble in water.
- Metronidazole solubility – soluble in dilute hydrochloric acid (1 in 2); sparingly soluble in water and in alcohol; slightly soluble in ether and in chloroform.
- Miconazole solubility – freely soluble in alcohol, in methanol, in isopropyl alcohol, in acetone, in propylene glycol, in chloroform, and in dimethylformamide; soluble in ether; insoluble in water.
- Miconazole Nitrate solubility – freely soluble in dimethyl sulfoxide; soluble in dimethylformamide; sparingly soluble in methanol; slightly soluble in alcohol, in chloroform, and in propylene glycol; very slightly soluble in water and in isopropyl alcohol; insoluble in ether.
- Midazolam solubility – insoluble in water.
- Minoxidil solubility – soluble in alcohol and in propylene glycol; sparingly soluble in methanol; slightly soluble in water; practically insoluble in chloroform, in acetone, in ethyl acetate, and in hexane.
- Mirtazapine solubility – freely soluble in methanol and in toluene; soluble in ethyl ether; sparingly soluble in n-hexane; practically insoluble in water.
- Misoprostol solubility – very slightly soluble in water.
- Mometasone Furoate solubility – Soluble in acetone and in methylene chloride.
- Montelukast Sodium solubility – freely soluble to very soluble in alcohol; freely soluble in water and in methylene chloride.
- Moxifloxacin Hydrochloride solubility – soluble in 0.1 N sodium hydroxide; sparingly soluble in water and in methanol; slightly soluble in 0.1 N hydrochloric acid, in dimethylformamide, and in alcohol; practically insoluble in methylene chloride, in acetone, in ethyl acetate, and in toluene; insoluble in tert-butyl methyl ether and n-heptane.
- Mupirocin solubility – freely soluble in acetone, in chloroform, in dehydrated alcohol, and in methanol; slightly soluble in ether; very slightly soluble in water.
- Myristic Acid solubility – soluble in alcohol, in chloroform, and in ether; practically insoluble in water. NF category: Antifoaming agent; emulsifying agent; lubricant.
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