This pharmaceutical solubility database contains the aqueous and chemical solubility of API and Excipients commonly used in pharmaceutical industry.
- Nabumetone solubility – freely soluble in acetone; sparingly soluble in alcohol and in methanol; practically insoluble in water.
- Nadolol solubility – freely soluble in alcohol and in methanol; soluble in water at pH 2; slightly soluble in chloroform, in methylene chloride, in isopropyl alcohol, and in water (between pH 7 and pH 10).
- Nalidixic Acid solubility – soluble in chloroform, in methylene chloride, and in solutions of fixed alkali hydroxides and carbonates; slightly soluble in acetone, in alcohol, in methanol, and in toluene; very slightly soluble in ether and in water.
- Naloxone Hydrochloride solubility – soluble in water, in dilute acids, and in strong alkali; slightly soluble in alcohol; practically insoluble in ether and in chloroform.
- Naproxen solubility – soluble in chloroform, in dehydrated alcohol, and in alcohol; sparingly soluble in ether; practically insoluble in water.
- Naproxen Sodium solubility – soluble in water and in methanol; sparingly soluble in alcohol; very slightly soluble in acetone; and practically insoluble in chloroform and in toluene.
- Natamycin solubility – soluble in glacial acetic acid and in dimethylformamide; slightly soluble in methanol; practically insoluble in water.
- Neomycin Sulfate solubility – freely soluble in water; very slightly soluble in alcohol; insoluble in acetone, in chloroform, and in ether.
- Niacin solubility – freely soluble in boiling water, in boiling alcohol, and in solutions of alkali hydroxides and carbonates; sparingly soluble in water; practically insoluble in ether.
- Niacinamide solubility – freely soluble in water and in alcohol; soluble in glycerin.
- Nifedipine solubility – freely soluble in acetone; practically insoluble in water.
- Nitrofurantoin solubility – soluble in dimethylformamide; very slightly soluble in water and in alcohol.
- Nizatidine solubility – freely soluble in chloroform; soluble in methanol; sparingly soluble in water.
- Norfloxacin solubility – freely soluble in acetic acid; sparingly soluble in chloroform; slightly soluble in acetone, in water, and in alcohol; very slightly soluble in methanol and in ethyl acetate; insoluble in ether.
- Norgestrel solubility – freely soluble in chloroform; sparingly soluble in alcohol; insoluble in water.
- Nystatin solubility – freely soluble in dimethylformamide and in dimethyl sulfoxide; very slightly soluble in methanol; practically insoluble or insoluble in water, in alcohol, in n-propyl alcohol, in n-butyl alcohol, in chloroform, and in ether.
- Octyldodecanol solubility – soluble in alcohol and in ether; insoluble in water.
- Ofloxacin solubility – sparingly soluble in chloroform; slightly soluble in alcohol, in methanol, and in water.
- Olanzapine solubility – soluble in n-propanol; sparingly soluble in acetonitrile; slightly soluble in methanol and in dehydrated alcohol; practically insoluble in water.
- Oleic Acid solubility – practically insoluble in water.
- Olmesartan Medoxomil solubility – sparingly soluble in methanol; practically insoluble in water.
- Olopatadine Hydrochloride solubility – very soluble in formic acid; sparingly soluble in water; very slightly soluble in dehydrated alcohol.
- Omeprazole solubility – soluble in dichloromethane; sparingly soluble in methanol and in alcohol; very slightly soluble in water.
- Omeprazole Magnesium solubility – sparingly soluble in methanol; slightly soluble in alcohol; very slightly soluble in water and in dichloromethane.
- Ondansetron solubility – very soluble in acid solutions; sparingly soluble in water.
- Orbifloxacin solubility – soluble in acetic acid; very slightly soluble in methanol, in water, and in chloroform; practically insoluble in ethanol and in diethyl ether.
- Orlistat solubility – freely soluble in chloroform; very soluble in methanol and in alcohol; practically insoluble in water.
- Oseltamivir Phosphate solubility – freely soluble in water; soluble in methanol, in dimethyl sulfoxide, and in propylene glycol; sparingly soluble in dimethylformamide; slightly soluble in alcohol; very slightly soluble in isopropyl alcohol.
- Oxacillin Sodium solubility – freely soluble in water, in methanol, and in dimethyl sulfoxide; slightly soluble in absolute alcohol, in chloroform, in pyridine, and in methyl acetate; insoluble in ethyl acetate, in ether, in benzene, and in ethylene chloride.
- Oxaliplatin solubility – slightly soluble in water; very slightly soluble in methanol; practically insoluble in alcohol.
- Oxazepam solubility – slightly soluble in alcohol and in chloroform; very slightly soluble in ether; practically insoluble in water.
- Oxcarbazepine solubility – soluble in acetic acid; sparingly soluble in chloroform; practically insoluble in water.
- Oxfendazole solubility – slightly soluble in alcohol and in methylene chloride; practically insoluble in water.
- Oxycodone Hydrochloride solubility – soluble in water; slightly soluble in alcohol.
- Oxymetholone solubility – freely soluble in chloroform; soluble in dioxane; sparingly soluble in alcohol; slightly soluble in ether; practically insoluble in water.
- Oxymorphone Hydrochloride solubility – freely soluble in water; sparingly soluble in alcohol and in ether.
- Oxyquinoline Sulfate solubility – very soluble in water; freely soluble in methanol; slightly soluble in alcohol; practically insoluble in acetone and in ether.
- Oxytetracycline solubility – freely soluble in 3 N hydrochloric acid and in alkaline solutions; sparingly soluble in alcohol; very slightly soluble in water.
- Paclitaxel solubility – soluble in alcohol; insoluble in water.
- Paliperidone solubility – sparingly soluble in 0.1 N hydrochloric acid and in methylene chloride; slightly soluble in N,N-dimethylformamide and in tetrahydrofuran; practically insoluble in water, in 0.1 N sodium hydroxide, and in hexane.
- Palmitic Acid solubility – soluble in alcohol, in ether, and in chloroform; practically insoluble in water.
- Palonosetron Hydrochloride solubility – freely soluble in water; soluble in propylene glycol; slightly soluble in ethanol; very slightly soluble to slightly soluble in isopropyl alcohol.
- Pantoprazole Sodium solubility – freely soluble in water, in methanol, and in dehydrated alcohol; practically insoluble in hexane and in dichloromethane.
- Paraffin solubility – freely soluble in chloroform, in ether, in volatile oils, and in most warm fixed oils; slightly soluble in dehydrated alcohol; insoluble in water and in alcohol.
- Paricalcitol solubility – soluble in alcohol; insoluble in water.
- Paroxetine Hydrochloride solubility – soluble in methanol and in alcohol; slightly soluble in water.
- Penicillamine solubility – freely soluble in water; slightly soluble in alcohol; insoluble in chloroform and in ether.
- Pentazocine solubility – freely soluble in chloroform; soluble in alcohol, in acetone, and in ether; sparingly soluble in benzene and in ethyl acetate; practically insoluble in water.
- Pentobarbital solubility – very soluble in alcohol, in methanol, in ether, in chloroform, and in acetone; soluble in benzene; very slightly soluble in water and in carbon tetrachloride.
- Pentobarbital Sodium solubility – very soluble in water; freely soluble in alcohol; practically insoluble in ether.
- Phenobarbital solubility – soluble in alcohol, in ether, and in solutions of fixed alkali hydroxides and carbonates; sparingly soluble in chloroform; very slightly soluble in water.
- Phenobarbital Sodium solubility – very soluble in water; soluble in alcohol; practically insoluble in ether and in chloroform.
- Phenytoin solubility – soluble in hot alcohol; slightly soluble in cold alcohol, in chloroform, and in ether; practically insoluble in water.
- Pilocarpine solubility – soluble in water, in alcohol, and in chloroform; sparingly soluble in ether and in benzene; practically insoluble in petroleum ether.
- Pioglitazone Hydrochloride solubility – soluble in dimethylformamide; slightly soluble in dehydrated alcohol; very slightly soluble in acetone and in acetonitrile; practically insoluble in water; insoluble in ether.
- Piperacillin solubility – very soluble in methanol; slightly soluble in isopropyl alcohol; very slightly soluble in ethyl acetate and practically insoluble to very slightly soluble in water.
- Piperacillin Sodium solubility – freely soluble in water and in alcohol.
- Piperazine solubility – soluble in water and in alcohol; insoluble in ether.
- Piroxicam solubility – slightly soluble in alcohol and in aqueous alkaline solutions; very slightly soluble in water, in dilute acids, and in most organic solvents.
- Polyvinyl Alcohol solubility – freely soluble in water at room temperature.
- Potassium Benzoate solubility – freely soluble in water; soluble in 90% alcohol; sparingly soluble in alcohol.
- Potassium Bicarbonate solubility – freely soluble in water; practically insoluble in alcohol.
- Potassium Chloride solubility – freely soluble in water; insoluble in alcohol.
- Potassium Citrate solubility – freely soluble in water; very slightly soluble in alcohol.
- Potassium Hydroxide solubility – very soluble in boiling alcohol; freely soluble in water, in alcohol, and in glycerin.
- Potassium Iodide solubility – very soluble in water and even more soluble in boiling water; freely soluble in glycerin; soluble in alcohol.
- Povidone solubility – freely soluble in water, in methanol, and in alcohol; slightly soluble in acetone; practically insoluble in ether.
- Povidone-Iodine solubility – soluble in water and in alcohol; practically insoluble in chloroform, in carbon tetrachloride, in ether, in solvent hexane, and in acetone.
- Prazosin Hydrochloride solubility – slightly soluble in water, in methanol, in dimethylformamide, and in dimethylacetamide; very slightly soluble in alcohol; practically insoluble in chloroform and in acetone.
- Prednisolone solubility – soluble in methanol and in dioxane; sparingly soluble in acetone and in alcohol; slightly soluble in chloroform; very slightly soluble in water.
- Prednisolone Acetate solubility – slightly soluble in acetone, in alcohol, and in chloroform; practically insoluble in water.
- Prednisone solubility – slightly soluble in alcohol, in chloroform, in dioxane, and in methanol; very slightly soluble in water.
- Pregabalin solubility – freely soluble in water and in both basic and acidic aqueous solutions.
- Prilocaine solubility – very soluble in alcohol and in acetone; slightly soluble in water.
- Prilocaine Hydrochloride solubility – freely soluble in water and in alcohol; slightly soluble in chloroform; very slightly soluble in acetone; practically insoluble in ether.
- Probenecid solubility – soluble in dilute alkali, in chloroform, in alcohol, and in acetone; practically insoluble in water and in dilute acids.
- Progesterone solubility – soluble in alcohol, in acetone, and in dioxane; sparingly soluble in vegetable oils; practically insoluble in water.
- Promethazine Hydrochloride solubility – freely soluble in water, in hot dehydrated alcohol, and in chloroform; practically insoluble in ether, in acetone, and in ethyl acetate.
- Pyrazinamide solubility – sparingly soluble in water; slightly soluble in alcohol, in ether, and in chloroform.
- Pyridoxine Hydrochloride solubility – freely soluble in water; slightly soluble in alcohol; insoluble in ether.
- Pyrimethamine solubility – slightly soluble in acetone, in alcohol, and in chloroform; practically insoluble in water.
- Quetiapine Fumarate solubility – soluble in 0.1 N hydrochloric acid; slightly soluble in water, in alcohol, and in methanol.
- Quinidine Gluconate solubility – freely soluble in water; slightly soluble in alcohol.
- Quinine Sulfate solubility – slightly soluble in water, in alcohol, and in chloroform; very slightly soluble in ether.
- Ramipril solubility – freely soluble in methanol; sparingly soluble in water.
- Reserpine solubility – freely soluble in acetic acid and in chloroform; slightly soluble in benzene; very slightly soluble in alcohol and in ether; insoluble in water.
- Ribavirin solubility – freely soluble in water; slightly soluble in dehydrated alcohol.
- Riboflavin solubility – soluble in dilute solutions of alkalies; very slightly soluble in water, in alcohol, and in isotonic sodium chloride solution; insoluble in ether and in chloroform.
- Rifabutin solubility – soluble in chloroform and in methanol; sparingly soluble in alcohol; very slightly soluble in water.
- Rifampin solubility – freely soluble in chloroform; soluble in ethyl acetate and in methanol; very slightly soluble in water.
- Risedronate Sodium solubility – soluble in water and in aqueous solutions; insoluble in common organic solvents.
- Risperidone solubility – soluble in methylene chloride; sparingly soluble in alcohol; practically insoluble in water.
- Ritonavir solubility – freely soluble in methanol and in methylene chloride; very slightly soluble in acetonitrile; practically insoluble in water.
- Rivastigmine Tartrate solubility – very soluble in water and in methanol; very slightly soluble in ethyl acetate.
- Rizatriptan Benzoate solubility – soluble in water; sparingly soluble in alcohol; slightly soluble in methylene chloride.
- Ropivacaine solubility – freely soluble in methylene chloride; soluble in ethanol; practically insoluble in water.
- Rosiglitazone Maleate solubility – sparingly soluble in alcohol; slightly soluble in methylene chloride; practically insoluble to very slightly soluble in water.
- Rosuvastatin Calcium solubility – soluble in dimethyl formamide, in dimethyl sulfoxide, in acetone, and in acetonitrile; sparingly soluble in methanol; sparingly soluble to slightly soluble in water; slightly soluble in ethanol.
- Rotigotine solubility – soluble in anhydrous alcohol; very slightly soluble in heptane; practically insoluble in water.
- Roxadustat solubility – Soluble in organic solvents, poorly soluble in water.
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