Drugs
Hydrophilic and Hydrophobic Properties of Drug Substance
In pharmaceutical preparations, Hydrophobic and Hydrophilic properties play a crucial role in how drugs are formulated, delivered, and absorbed in the body. Hydrophobic Definition: Hydrophobic substances repel water and do not dissolve easily in it. They are often nonpolar molecules, like lipids or oils. Role in Pharmaceuticals Drug Solubility: Hydrophobic ... Read More
DAYVIGO (Lemborexant) for Insomnia
DAYVIGO (lemborexant) is indicated for the treatment of insomnia, characterized by difficulties with sleep onset and/or sleep maintenance. Lemborexant is a competitive antagonist of both orexin receptors, OX1R and OX2R, with a higher affinity for OX2R. It belongs to the pharmacologic class of orexin receptor antagonists. The orexin neuropeptide signaling ... Read More
QUTENZA (Capsaicin) For Neuropathic Pain
QUTENZA is indicated in adults for the treatment of neuropathic pain associated with postherpetic neuralgia and for neuropathic pain associated with diabetic peripheral neuropathy of the feet. Mechanism of action Only physicians or healthcare professionals are to administer and handle QUTENZA Usage − Administer it in a well-ventilated treatment area. ... Read More
MOUNJARO (Tirzepatide) | Drug Digest
MOUNJARO (tirzepatide injection) is indicated for once-weekly administration as an adjunct to diet and exercise to improve glycemic control for the treatment of adult patients with type 2 diabetes mellitus. Limitations of Use MOUNJARO is contraindicated in patients with a personal or family history of MTC and in patients with ... Read More
Hazardous Drugs Handling in Healthcare Settings
USP General Chapter- 800 provides standards for safe handling of hazardous drugs to minimize the risk of exposure to healthcare personnel, patients and the environment. The National Institute for Occupational Safety and Health (NIOSH) considers a drug to be hazardous if it exhibits one or more of the following characteristics ... Read More
Drug Development and Approval Process | Part III
When studying a new drug, it can sometimes take many years to learn whether a drug actually provides a real effect on how a patient survives, feels, or functions. A positive therapeutic effect that is clinically meaningful in the context of a given disease is known as clinical benefit. Mindful ... Read More
Drug Development and Approval Process | Part II
FDA Approval: What It Means FDA approval of a drug means that data on the drug’s effects have been reviewed by CDER, and the drug is determined to provide benefits that outweigh its known and potential risks for the intended population. The drug approval process takes place within a structured ... Read More
Drug Development and Approval Process | Part I
Developing New Drugs American consumers benefit from having access to the safest and most advanced pharmaceutical system in the world. The main consumer watchdog in this system is FDA’s Center for Drug Evaluation and Research (CDER). Drug companies seeking to sell a drug in the United States must first test ... Read More
Top 10 Drugs to Avoid During Pregnancy
In this article we provide you a list of top 10 drugs that are generally advised to be avoided during pregnancy due to potential risks. However, it’s crucial to consult with a qualified healthcare professional before making any decisions, as they can provide personalized advice based on your medical history ... Read More
Physicochemical Properties of Drugs
Physicochemical properties are all the physical and chemical properties of a drug, which are influence the drug performance or action. Various Physico-Chemical Properties of Drugs Thermodynamic properties Kinetic properties Spectroscopic properties Surface properties Mechanical properties Packing properties If a deficiency is detected, then the project team should decide on the ... Read More