Semi-solid

In semi-solid dosage forms such as creams, ointments, gels, and pastes, maintaining the stability of color and odor is crucial for product quality, safety, and patient acceptance. Causes of Color or Odor Changes Oxidation pH Changes Degradation of Active Ingredients Interaction Between Ingredients Microbial Contamination Light Exposure Temperature Fluctuations These ... Read More

Inadequate Drug Release Inadequate drug release in semi-solid dosage forms, such as creams, ointments, or gels, can significantly compromise the therapeutic efficacy of the product. Achieving the correct release profile is crucial for ensuring the desired pharmacological effect. Understanding the causes of inadequate drug release and addressing them through formulation ... Read More

Viscosity Changes Over Time in Semi-Solid Dosage Forms Viscosity, the thickness or flow resistance of a semi-solid dosage form, plays a critical role in the product’s performance and user experience. Over time, changes in viscosity can affect drug release, reduce efficacy, or cause instability. Understanding the causes of viscosity shifts ... Read More

Poor Stability in Semi-Solid Dosage Forms Stability is a critical factor in semi-solid dosage forms such as creams, ointments, and gels. Poor stability can lead to the degradation of the formulation, reduced efficacy, and potential harm to users. Understanding the causes and implementing appropriate solutions is essential for maintaining the ... Read More

Phase Separation of Semi-Solid Dosage Forms What is Phase Separation? Phase separation in semi-solid dosage forms occurs when the components of a formulation, which are intended to remain uniformly mixed, separate into distinct layers or phases. This disruption often leads to a product that no longer maintains its intended consistency, ... Read More

Are you ready to tackle some troubleshooting in semisolid dosage form manufacturing? As we gear up for the semifinal production stages, we must have a solid understanding of potential issues that may arise in the manufacturing process of semisolid dosage forms such as creams, ointments, and gels. From formulation challenges ... Read More