The solubility of drug molecule is one of the most challenging aspect in formulation development. It is crucial to ensure the right concentration of a drug gets into the bloodstream so the bioavailability of the drug causes the desired pharmacological response. Therefore, using a variety of techniques to improve solubility helps drug companies launch a…
Drug discovery is part luck and part structured investigation. At the beginning of the 19th century it was largely carried out by individuals but it now requires teamwork, the members of the team being specialists in various fields, such as medicine, biochemistry, chemistry, computerized molecular modeling, pharmaceutics, pharmacology, microbiology, toxicology, physiology and pathology. The approach…
Solubility is defined as the upper limit of solute that can be dissolved in a given amount of solvent at equilibrium. It is also called the ability of substance to dissolve in a solvent.orThe solubility is defined as the concentration of the solute in solution when it is in equilibrium with the solid substance at…