When developing liquid oral dosage forms, preformulation studies are key to ensuring the product’s stability, efficacy, and patient compliance. These studies help identify the ideal formulation parameters, including:
Solubility & Stability: Assessing the drug’s solubility in different solvents and conditions to predict shelf-life and storage needs.
pH Sensitivity: Understanding the drug’s stability across pH ranges and selecting the optimal pH for formulation.
Excipient Compatibility: Ensuring excipients don’t interact negatively with the active pharmaceutical ingredient (API).
Viscosity & Rheology: Determining the right viscosity for ease of administration and absorption.
By conducting thorough preformulation research, we can design liquid dosage forms that not only meet regulatory standards but also improve patient adherence and overall therapeutic outcomes.
Read also: Rheology in Pharmaceuticals
Resource Person: Janki Parmar