Dissolution
Surfactants in Dissolution
We have many factors to consider when making a dissolution method. What apparatus, speed, filter choice, etc. Of these factors, the one I get the most questions about is media selection – especially surfactants in media selection. So, what is a surfactant and why do we use them? What do ... Read More
Importance of pKa Value in Selection of Dissolution Media
There is a question: How pKa value helps in selection of Dissolution Media during Formulation & Analytical Development? For Dissolution, Ionized form of a drug is required to be solubilized & released passively into dissolution medium. While, For Absorption, only unionized form of drug is important to be absorbed passively ... Read More