Blending or Mixing are the reorientation of particles relative to one another in order to achieve uniformity.
Types of Blending
- Diffusion Blending (Tumble)
- Convection Mixing
- Pneumatic Mixing
Operating Principles of Blending
Diffusion Blending (Tumble)
Particles are reoriented in relation to one another when they are placed in random motion and inter particular friction is reduced as the result of bed expansion (usually within a rotating container); also known as tumble blending.
Convection Mixing
Particles are reoriented in relation to one another as a result of mechanical movement; also known as paddle or plow mixing.
Pneumatic Mixing
Particles are reoriented in relation to one another as a result of the expansion of a powder bed by gas.
Types of Blenders or Mixers in Pharmaceutical Industry
1. Diffusion Mixers (Tumble)
Diffusion mixer subclasses primarily are distinguished by geometric shape and the positioning of the axis of rotation.
- V-blenders
- Double Cone Blenders
- Slant Cone Blenders
- Cube Blenders
- Bin Blenders
- Horizontal/Vertical/Drum Blenders
- Static Continuous Blenders
- Dynamic Continuous Blenders
2. Convection Mixers
Convection blender subclasses primarily are distinguished by vessel shape ad impeller geometry:
- Ribbon Blenders
- Orbiting Screw Blenders
- Planetary Blenders
- Forberg Blenders
- Horizontal Double Arm Blenders
- Horizontal High Intensity Mixers
- Vertical High Intensity Mixers
3. Pneumatic Mixers
Although pneumatic mixers may differ from one another in vessel geometry, air nozzle type, and air nozzle configuration, no pneumatic mixer subclasses have been identified.
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