Tablet
Can You Crush a Tablet Before Taking It?
Whether it’s for your grandma who can’t swallow, or your child who hates medicine… many of us have crushed tablets thinking it’s harmless. But did you know? Not every tablet is made for that. Let’s break it down simply: Tablets You Should NEVER Crush: 1. Enteric-Coated Tablets (EC) 2. Extended-Release ... Read More
Can You Store Tablets in the Fridge?
Short Answer: No, unless the label or pharmacist says so. Why You Shouldn’t Refrigerate Tablets? 1. Condensation = Killer 2. Not Designed for Cold 3. Packaging Breakdown When Fridge Is Okay for Medicines? Only store in the fridge if the label or pharmacist clearly says: “Store at 2–8°C” Examples: Insulin, ... Read More
The Science Behind Effervescent Tablets
Ever marveled at the rapid fizz of an effervescent tablet? Behind that effervescence lies a meticulously crafted blend of excipients, each serving a crucial role in the tablet’s formulation. Acidulants: Think citric acid or tartaric acid. These key players react with bicarbonates, like sodium bicarbonate or potassium bicarbonate, triggering the ... Read More
Powder Shape and Their Effect on Tablet Properties
The pharmaceutical industry relies heavily on powders for the formulation of solid dosage forms, particularly tablets. Powder properties, including particle size and shape, directly affect the manufacturing process and the performance of the final product. While particle size has been extensively studied, the influence of particle shape has garnered increasing ... Read More
How do We Ensure that Split Tablets Maintain Dose Accuracy and Stability?
For those who need flexible dosing, tablet splitting (for tablets with a functional score-line) can be helpful, but it’s essential to ensure each piece is consistent and effective. Here’s a quick look at the *key tests and acceptance criteria to assess splitting of scored immediate-release tablets. To ensure quality and ... Read More
Basics of Tablet Tooling
Tooling can be defined as tools to craft a particular shape. Tableting tools i.e., Punches and dies are essential tools to shape any granules into a solid dosage form by applying compaction force in a compression machine. Any shape be it round, oblong or bullet shape or any special shape ... Read More
Coating Process in Pharmaceutical Industry
Although both sugar coating and film coating are utilized by a significant number of pharmaceutical companies worldwide, the film-coating process is the one most often preferred today. Film coating was formally introduced into the pharmaceutical industry in the middle of the last century. It should be noted that there has ... Read More
Compression Process in Tablet Manufacturing
Compression or compaction is the pharmaceutical unit operation of applying pressure or force to the powder to densify it and generate the physical bonds between the powder particles. The critical parameters of this operation are (1) the material properties of the particles being compacted and (2) the equipment used for ... Read More
Blending Process in Pharmaceutical industry
Blending or Mixing are the reorientation of particles relative to one another in order to achieve uniformity. Types of Blending Operating Principles of Blending Diffusion Blending (Tumble) Particles are reoriented in relation to one another when they are placed in random motion and inter particular friction is reduced as the ... Read More
Milling Process in Pharmaceutical Industry
Milling is a mechanical process of breaking particles into smaller pieces via one or more particle size reduction mechanisms. Types of Milling Milling Operation Principles Milling Equipment Classifications 1. Fluid Energy Mills Fluid energy mill subclasses have no moving parts and primarily are distinguished from one another by the configuration ... Read More
Granulation Process in Pharmaceutical Tablet Manufacturing
Granulation is the process of creating granules. The powder morphology is modified through the use of either a liquid that causes particles to bind through capillary forces or dry compaction forces. Importance of Granulation in Pharmaceutical Industry The granulation process will result in one or more of the following powder ... Read More